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Year : 2017  |  Volume : 35  |  Issue : 1  |  Page : 124-128

Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia


1 Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
2 Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia

Correspondence Address:
Kwai Lin Thong
Faculty of Science, Institute of Biological Sciences, University of Malaya, 50603 Kuala Lumpur
Malaysia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmm.IJMM_15_458

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Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G.






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2004 - Indian Journal of Medical Microbiology
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